namespace RequestResponse.Messages
{
    public class MyMessage 
    {
        public string Text { get; set; }
    }
}

using System;
using log4net;
using log4net.Config;
using Shuttle.Core.Host;
using Shuttle.Core.Infrastructure;
using Shuttle.Core.Infrastructure.Log4Net;
using Shuttle.ESB.Core;
using Shuttle.ESB.Modules.ActiveTimeRange;

namespace RequestResponse.Server
{
	public class ServiceBusHost : IHost, IDisposable
	{
		private static IServiceBus bus;

		public void Start()
		{
			Log.Assign(new Log4NetLog(LogManager.GetLogger(typeof(ServiceBusHost))));

			bus = ServiceBus.Create().Start();

            Console.WriteLine("#########server-end bus instance has started");
		}

		public void Dispose()
		{
			bus.Dispose();
			LogManager.Shutdown();
		}
	}
}

using System;
using System.Text;
using RequestResponse.Messages;
using Shuttle.Core.Infrastructure;
using Shuttle.ESB.Core;

namespace RequestResponse.Server
{
    public class ServerMessageHandler : IMessageHandler<MyMessage>
	{
		private int received;

        public void ProcessMessage(HandlerContext<MyMessage> context)
		{
            //伺服器端接受到訊息
            Console.WriteLine("【SERVER-END RECEIVE A MSG，Content："+ context.Message.Text+ "】");
           
            //伺服器端傳送迴應訊息
			context.Bus.SendReply(new MyMessage
					{
						Text = "I have recwived your msg"
					});
		}

        public bool IsReusable
        {
            get { return true; }
        }
	}
}

<?xml version="1.0"?>
<configuration>
	<configSections>
		<section name="serviceBus" type="Shuttle.ESB.Core.ServiceBusSection, Shuttle.ESB.Core"/>
    <section name="log4net" type="log4net.Config.Log4NetConfigurationSectionHandler, log4net"/>
	</configSections>

	<serviceBus>
    <control workQueueUri="msmq://./requestresponse-server-control-inbox-work" errorQueueUri="msmq://./shuttle-samples-error" durationToSleepWhenIdle="250ms*25,500ms*10,1s" threadCount="1"/>
    <inbox workQueueUri="msmq://./requestresponse-server-inbox-work" errorQueueUri="msmq://./shuttle-samples-error" durationToSleepWhenIdle="250ms,1s" durationToIgnoreOnFailure="1s" threadCount="1"/>
	</serviceBus>

  <log4net>
    <appender name="ConsoleAppender" type="log4net.Appender.ColoredConsoleAppender">
      <layout type="log4net.Layout.PatternLayout">
        <conversionPattern value="%d [%t] %-5p %c - %m%n"/>
      </layout>
    </appender>
    <appender name="RollingFileAppender" type="log4net.Appender.RollingFileAppender">
      <file value="logs\request-response-server"/>
      <appendToFile value="true"/>
      <rollingStyle value="Date"/>
      <maxSizeRollBackups value="10"/>
      <maximumFileSize value="100000KB"/>
      <datePattern value="-yyyyMMdd.'log'"/>
      <param name="StaticLogFileName" value="false"/>
      <layout type="log4net.Layout.PatternLayout">
        <conversionPattern value="%d [%t] %-5p %c - %m%n"/>
      </layout>
    </appender>
    <root>
      <level value="TRACE"/>
      <appender-ref ref="ConsoleAppender"/>
      <appender-ref ref="RollingFileAppender"/>
    </root>
  </log4net>

<startup><supportedRuntime version="v4.0" sku=".NETFramework,Version=v4.0"/></startup></configuration>

using System;
using log4net;
using RequestResponse.Messages;
using Shuttle.Core.Infrastructure;
using Shuttle.Core.Infrastructure.Log4Net;
using Shuttle.ESB.Core;

namespace RequestResponse.Client
{
	internal class Program
	{
		private static void Main()
		{
            Log.Assign(new Log4NetLog(LogManager.GetLogger(typeof(Program))));

			var bus = ServiceBus.Create().Start();

            Console.WriteLine("###### Client bus started. Press CTRL+C to stop.");
            Console.WriteLine();
			Console.WriteLine("@Press enter to send a message to the server.");
			Console.WriteLine();

            while (true)
            {
                Console.ReadLine();
                //將訊息傳送出去
                bus.Send(new MyMessage{Text = "Client Massage"});
            }
		}
	}
}

using System;
using RequestResponse.Messages;
using Shuttle.Core.Infrastructure;
using Shuttle.ESB.Core;

namespace RequestResponse.Client
{
    public class ClientMessageHandler : IMessageHandler<MyMessage>
    {
		public void ProcessMessage(HandlerContext<MyMessage> context)
    	{
            //客戶端接收到訊息
            Console.WriteLine("【Client-END RECEIVE A MSG, Content:"+ context.Message.Text +"】");
		}

        public bool IsReusable
        {
            get { return true; }
        }
    }
}

<?xml version="1.0"?>
<configuration>
	<configSections>
		<section name="serviceBus" type="Shuttle.ESB.Core.ServiceBusSection, Shuttle.ESB.Core"/>
    <section name="log4net" type="log4net.Config.Log4NetConfigurationSectionHandler, log4net"/>
  </configSections>

  <serviceBus>
		<messageRoutes>
			<messageRoute uri="msmq://./requestresponse-server-inbox-work">
				<add specification="StartsWith" value="RequestResponse"/>
			</messageRoute>
		</messageRoutes>
		<inbox workQueueUri="msmq://./requestresponse-client-inbox-work" journalQueueUri="msmq://./requestresponse-client-inbox-journal" errorQueueUri="msmq://./shuttle-samples-error"/>
		<outbox workQueueUri="msmq://./requestresponse-client-outbox-work" errorQueueUri="msmq://./shuttle-samples-error"/>
	</serviceBus>

  <log4net>
    <appender name="ConsoleAppender" type="log4net.Appender.ColoredConsoleAppender">
      <layout type="log4net.Layout.PatternLayout">
        <conversionPattern value="%d [%t] %-5p %c - %m%n"/>
      </layout>
    </appender>
    <appender name="RollingFileAppender" type="log4net.Appender.RollingFileAppender">
      <file value="logs\request-response-server"/>
      <appendToFile value="true"/>
      <rollingStyle value="Date"/>
      <maxSizeRollBackups value="10"/>
      <maximumFileSize value="100000KB"/>
      <datePattern value="-yyyyMMdd.'log'"/>
      <param name="StaticLogFileName" value="false"/>
      <layout type="log4net.Layout.PatternLayout">
        <conversionPattern value="%d [%t] %-5p %c - %m%n"/>
      </layout>
    </appender>
    <root>
      <level value="TRACE"/>
      <appender-ref ref="ConsoleAppender"/>
      <appender-ref ref="RollingFileAppender"/>
    </root>
  </log4net>

<startup><supportedRuntime version="v4.0" sku=".NETFramework,Version=v4.0"/></startup></configuration>